Cell Based Assays
Abcam Human ABCC2 knockout A549 cell lysate.
Human ABCC2 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PVR (Poliovirus Receptor) knockout A549 cell lysate.
Human PVR (Poliovirus Receptor) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC RK-33 5mg 1070773-09-9
RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
AdipoGen WP1130
Chemical. CAS 856243-80-6. Formula C19H18BrN3O. MW 384.3. WP1130 is a second-generation tyrphostin derivative initially identified as a JAK2 signaling inhibitor through JAK2 ubiquitination that reduces STAT activation stimulated by cytokines such as IL-6 and IL-3 through the rapid down-regulation of upstream JAK kinases. WP1130 has also been identified as a partially selective cell permeable deubiquitinating enzyme/deubiquitinase DUB inhibitor that directly inhibits DUB activity of USP9x, USP5, USP14, USP24, UCH37, UCHL1 and UCHL5, leading to rapid accumulation of polyubiquitinated K48/K63-linked proteins into juxtanuclear aggresomes and tumor cell apoptosis, accounting for its anti-cancer properties. Through this mechanism, WP1130 has been shown to downregulate the antiapoptotic proteins Bcr/Abl and Jak2 and to upregulate the proapoptotic proteins MCL-1 and p53.
Cayman Chemical Z-VAD-AMC (acetate), Purity: ≥95%, 5 mg
A caspase-1 fluorogenic substrate; upon enzymatic cleavage, AMC is released and its fluorescence can be used to quantify enzyme activity; ex/em = 340-360/440-460 nm, respectively
Medchemexpress LLC HY-100894 1mg Medchemexpress, Biotin-VAD-FMK CAS:1135688-15-1 Purity:>98%
Medchemexpress, HY-100894 1mg Biotin-VAD-FMK CAS:1135688-15-1 Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cell Signaling Technology PathScanR RP Cleaved Caspase-9 Asp315 Sandwich ELISA Kit 20 Kit
PathScanR RP Cleaved Caspase-9 Asp315 Sandwich ELISA Kit 20 Kit
Abcam Human CD47 knockout HEK-293T cell lysate.
Human CD47 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc ANNEXIN V AF488 7 AAD APOP KIT
5000265218 ANNEXIN V AF488 7 AAD APOP KIT